When analyzing TCGA datasets for skin cutaneous melanoma (SKCM, n = 470 patients), breast invasive carcinoma (BRCA, n = 1098), head and neck squamous cell carcinoma (HNSC, n = 528), and lung adenocarcinoma (LUAD, n = 585), we observed a positive correlation between the three chemokines XCL1 , XCL2 , and CCL5 that was highly significant in each dataset ( Figures 6 B and S6 A), consistent with the notion that they might all be produced by the same intratumoral cell type.
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NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control.
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