marginally significantP = 0.094
Using permutation tests based on random reshuffling of sample labels when comparing G3 control samples to either G3 drought or SA samples ( supplementary text S3 , Supplementary Material online), we found a significant reduction in the proportion of 24 nt sRNAs after grandparental SA treatment (bootstrap test, P = 0.035), and also marginally significant shifts in 24 nt sRNAs after grandparental drought treatment (bootstrap test, P = 0.094) and in 21 nt sRNAs after grandparental SA treatment (bootstrap test, P = 0.086) ( fig. 1 A and D ).