Intervention effect of total flavonoids of ilex pubesceus on tolerant rat models under cerebral anoxia.

Compared with the pretreatment model group, the IL-1β content and TNF-α content in the brain homogenate of the rats in the large-dosage, medium-dosage and small-dosage groups of total flavonoid of ilex pubesceus and Ginaton group showed an increasing trend, but had no statistical difference ( P > .05); compared with the ischemia-reperfusion group, the IL-1β content and TNF-α content ( P < .01) in the brain homogenate of the rats in the large-dosage group of total flavonoid of ilex pubesceus and Ginaton group significantly increased, the IL-1β content

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But in the pretreatment model group, the neurological deficit score only showed a decreasing trend and was not significantly different ( P > .05). 5.2 Effect of total flavonoids of ilex pubesceus on whole blood viscosity and plasma viscosity of the rat models of cerebral ischemic tolerance Table 2 showed that: the whole blood viscosity and plasma viscosity of the rats in the sham-operated group significantly increased ( P < .01), showing that the model was made successfully.

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