Although the cell length and aspect ratio slightly increased with S1P and VEGF in the monoculture system ( Figure 5 C), the 3D culture system revealed a highly significant effect of the growth factors in the co-culture group for the formation of the blood-vessel-like network.
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Promotion of Vascular Morphogenesis of Endothelial Cells Co-Cultured with Human Adipose-Derived Mesenchymal Stem Cells Using Polycaprolactone/Gelatin Nanofibrous Scaffolds.
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