Hereditary cancer genes are highly susceptible to splicing mutations.

PLoS Genet · 2018 · PMC5854443 · PMID 29505604

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highly significantno p-value reported

Highly significant enrichment in the overlap between the targets of these driver mutations and SSM-prone genes was observed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.