highly significantp < 0.0001
The correlation of F rest with F ref was highly significant (HA 1: Spearman r = 0.92, p < 0.0001; HA 2: Spearman r = 0.84, p < 0.0001) and the regression lines were almost parallel to the bisector, indicating that F rest and F ref were tightly coupled (Fig. 5 ).