Palladium Nanoparticles: Toxicological Effects and Potential Implications for Occupational Risk Assessment.

Repeated injections of Pd-NPs, in fact, induced a decreasing trend in serum levels in most of the cytokines investigated, with the highest concentration (12 μg/kg) determining significant inhibitory effects compared to controls, supporting a more complex interaction between these nanomaterials and the immune system, related also to the time points investigated.

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Results showed an increasing trend in urinary Pd levels demonstrating that Pd urinary concentrations were directly associated with the administered doses.

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