Although there was a slight trend toward inhibition of B cell depletion in one donor, there were no statistically significant effects with idelalisib across the range of obinutuzumab concentrations.
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The PI3Kδ-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo.
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