Moreover, B0213Δprn induces significantly more expression of TLR1 , TLR5 , and TLR6 (9.5, 4.7, and 2.4 fold respectively) and an increasing trend for TLR2 (3.1 fold) compared to B0213.
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Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor.
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