Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression.

PLoS One · 2018 · PMC5862471 · PMID 29561882

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highly significantno p-value reported

Top ASP-induced canonical pathways generated in IPA revealed a highly significant upregulation of adrenal genes involved in glutamate and GABAergic signaling, together with a downregulation in FXR/RXR pathway genes ( Fig 4B ).

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