Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis.

PLoS One · 2018 · PMC5863946 · PMID 29565998

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highly significantno p-value reported

These differences were highly significant and reflect a ≥ 99.9% reduction in parasite burden in the K11777 treated group.

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