Yet, we did not observe a definite trend relating an increase in cell number with higher GBM migration, suggesting that although physical changes of the matrix might be present, the effect of stromal cells on migration is mainly due to cell-cell specific interactions, especially during short period of times.
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Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition.
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