Impact of hypoglycemic episodes on health-related quality of life of type-2 diabetes mellitus patients: development and validation of a specific QoLHYPO^© questionnaire.

Minimal clinically important difference Minimal clinically important difference (MCID), defined as the smallest change in score in the questionnaire that could be considered significant, was based on the above-mentioned anchor questions, which allowed selecting patients who had experienced an improvement (“better”) [ 47 ].

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