Environmentally prevalent polycyclic aromatic hydrocarbons can elicit co-carcinogenic properties in an in vitro murine lung epithelial cell model.

While these Cx43 protein expression levels did not significantly differ between B[ a ]P alone or the combination groups, there was a decreasing trend in Cx43 expression at the B[a]P with 5 μM LMW binary PAH mixture group supporting the reduced GJIC activity and mRNA expression observed at these concentrations (Fig. 6 a).

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