A hidden Markov tree model for testing multiple hypotheses corresponding to Gene Ontology gene sets.

BMC Bioinformatics · 2018 · PMC5869792 · PMID 29587646

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highly significantno p-value reported

If the top-down procedure were used, the highly significant GO term “GO:0031117” would never be tested even at an FWER level of 0.2.

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