HiC-spector: a matrix library for spectral and reproducibility analysis of Hi-C contact maps.

Bioinformatics · 2017 · PMC5870694 · PMID 28369339

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The leading eigenvector refers to the steady state distribution; the next few eigenvectors correspond to the slower decay modes of the random walk process and capture the densely interacting domains that are highly significant in contact maps.

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