Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21.

PLoS One · 2018 · PMC5870938 · PMID 29584757

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highly significantno p-value reported

Altered HERVH expression in trisomic iPSCs Examination of the accumulation of repetitive element transcripts revealed a highly significant decrease in transcripts from the endogenous retrovirus HERVH in the trisomic iPSCs.

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