Proton Pump Inhibitors Intake and Iron and Vitamin B12 Status: A Prospective Comparative Study with a Follow up of 12 Months.

The findings from this study indicate significant changes in iron body stores (serum ferritin levels) among PPIs and specific PPIs subgroups between the two time points, while no significant changes in serum iron levels (except for borderline significance when PPIs users as a single entity), and speak for pre-latent iron deficiency that is actually the initial phase in the pathogenesis of iron deficiency anemia.

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