The demand for parallel, multiplex analysis of protein biomarkers from very small biospecimens obtained at time of surgery, or through blood/CSF samples during follow-up, represented for years an increasing trend, mostly aimed at creating spatially encoded microarrays able to capture multiple proteins of interests in a cell lysate all at once [ 29 ].
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How Nanotechnology and Biomedical Engineering Are Supporting the Identification of Predictive Biomarkers in Neuro-Oncology.
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