borderline significantP = 0.05
A borderline significant protective effect of alignment in the FOH in the aligned group [HR after alignment with BL as the referent 0.22 (95% CI 0.05 to 1.03); P = 0.05] is contrasting a non-significant but rather adverse effect of alignment in the AT analysis [HR after alignment with BL as the referent 1.60 (95% CI 0.52 to 4.89); P = 0.41].