marginally significantP = 0.054
These tests cannot reject a model of neutral evolution for Old World monkey and hominoid H2A.L genes ( d N / d S = 0.79, P = 0.49 in a test to reject neutral evolution) (see Methods) but provide marginally significant evidence for purifying selection in the New World monkey H2A.L genes that lack C-terminal extensions ( d N / d S = 0.62, P = 0.054).