Remarkably, the reported hRAD51‐dsDNA filament length of 1.5 nm per hRAD51 monomer (Ristic et al , 2005 ) matches that of the ATP‐compact state for hRAD51‐ssDNA (1.4 ± 0.3 nm); this correspondence might be significant for homology search and strand exchange processes during homologous recombination.
← all excerpts
Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA.
1
—
—