The prevalence of brain abnormalities in boys with central precocious puberty may be overestimated.

PLoS One · 2018 · PMC5882100 · PMID 29614125

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an increasing trendno p-value reported

Our data revealed an increasing trend in the number of boys with CPP and the number of incidental findings since 2012.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.