However, some epidemiological studies report a seropositivity peak between 30 and 44 years and then a decline through older ages [9] , [10] , [17] and others report an increasing trend of seropositivity as age increases [21] , [22] .
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Seroprevalence of HPV 6, 11, 16 and 18 and correlates of exposure in unvaccinated women aged 16-64 years in Puerto Rico.
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Our study showed a decreasing trend in HPV seropositivity with increasing age for HPV 16 and HPV 18; higher HPV 16 seroprevalence was also previously reported in younger Puerto Rican women, although no significant differences were observed across age-groups in that smaller study [12] .