A point of interest is that qnr genes in natural isolates are known to be located on many different plasmid backbones, 7 raising the possibility that there might be significant natural variation in drug susceptibility associated with differences in plasmid copy number or mechanisms controlling gene expression.
← all excerpts
Increased expression of Qnr is sufficient to confer clinical resistance to ciprofloxacin in Escherichia coli.
1
—
—