Biomarker potential of ST6GALNAC3 and ZNF660 promoter hypermethylation in prostate cancer tissue and liquid biopsies.

Although ZNF660 was only borderline significant or nonsignificant after adjustment for routine clinicopathological factors in multivariate cox regression analysis ( P = 0.092/0.165; Table 2 ), Harrell's C‐index increased in both cohorts by the addition of ZNF660 to a multivariate model based on clinicopathological variables only (Table 2 ), suggesting improved predictive accuracy.

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