The Association between PARP1 and LIG3 Expression Levels and Chromosomal Translocations in Acute Myeloid Leukemia Patients.

Cell J · 2018 · PMC5893292 · PMID 29633598

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borderline significanceno p-value reported

For instance, when all patients with at least one translocation are compared, only LIG3 is overexpressed, however, when patients with two or more translocations are compared with those with an isolated translocation, both genes are significantly up- regulated with PARP1 showing borderline significance, suggesting that PARP1 is most likely associated with severity of genetic risk.

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