While a decreasing trend in the levels of p-YAP was observed in cells pretreated with Rho kinase and MLCK inhibitors before addition of LPA, the changes were not significant relative to the appropriate controls treated with inhibitor alone.
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Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells.
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