Barely Significant
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Combination Varenicline/Bupropion Treatment Benefits Highly Dependent Smokers in an Adaptive Smoking Cessation Paradigm.

Nicotine Tob Res · 2017 · PMC5896474 · PMID 29054128

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a nonsignificant trendno p-value reported
Figure 1 depicts the abstinence rates in the various subgroups and shows the substantial differential effect of combination treatment in highly dependent smokers as well as a nonsignificant trend for a greater effect in patch nonresponders.

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