Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.

Nat Med · 2018 · PMC5896729 · PMID 29529015

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highly significantno p-value reported

Strikingly, PDGF-CC showed a highly significant correlation to the basal-like markers cytokeratin (CK) 5/6 and epidermal growth factor receptor (EGFR), while low expression of PDGF-CC denoted hormone receptor-positive tumors expressing FOXA1, ERα and PgR ( Table 2 ).

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