Barely Significant
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Sub-acute administration of lower doses of nicotine caused sex-dependent improvement of renal function in Wistar rats.

Toxicol Rep · 2017 · PMC5897321 · PMID 29657920

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may be significantno p-value reported
A sensitive indicator of an effect of an experimental compound may be significant differences in organ weights between treated and untreated animals in the absence of morphological changes [60] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.