Predictive and mechanistic multivariate linear regression models for reaction development.

56 Depicted by a correlation between the logarithmic values of the enantiomeric products and σ , a pronounced trend was revealed where manganese-salen catalyst 26 with electron-donating para -substituents resulted in higher enantioselectivities in the epoxidation reaction of 2,2-dimethylchromene 27 ( Fig. 5C ) and cis -β-methylstyrene 29 ( Fig. 5D ).

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