Barely Significant
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Evaluation of Detection Methods and Values of Circulating Vascular Endothelial Growth Factor in Lung Cancer.

J Cancer · 2018 · PMC5907677 · PMID 29675110

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an increasing trendno p-value reported
Six 91 , 75 , 67 , 79 , 83 - 84 showed that the baseline VEGF level expressed had a significant decrease after treatment; of the other three, one 70 was about lymph node metastasis diagnosis, another one 89 showed an increasing trend of the VEGF level during treatment, and the last one 76 showed no change during therapy, while the VEGF baseline level was associated with response to therapy 76 , 89 .

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a decreasing trendno p-value reported
Two of the multicenter trials 86 , 89 found that the plasma level of VEGFR-2 expressed a decreasing trend during treatment, and one 86 showed the baseline VEGFR-2 level correlated with the response to treatment, while the other did not 89 .

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.