RNA-Sequencing Reveals Unique Transcriptional Signatures of Running and Running-Independent Environmental Enrichment in the Adult Mouse Dentate Gyrus.

Front Mol Neurosci · 2018 · PMC5908890 · PMID 29706867

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0506

boldest claim

The sentences

highly significantp < 10 -9actually significant

The transcriptional changes in CE mice were statistically highly significant (ranging from p < 10 -9 to 10 -5 ), and involved ECM processes related to collagen synthesis/modification/assembly and intracellular signaling via the PIP2/PLCg/DAG/IP3 pathway.

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extremely significantp = 0.0004actually significant

In the 4-arm variation ( Figure 1M ), the group effect was very significant [ F (2,230) = 5.822, p = 0.0034] and the trial # effect was extremely significant [ F (9,230) = 3.552, p = 0.0004].

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nearly reached significancep = 0.0506so close (0.05 < p ≤ 0.1)

At the 1 h time-point, the SOC group showed a statistically significant performance above chance and the LD group nearly reached significance (LD, p = 0.0506; SOC, p = 0.0125; RUN, p = 0.7442).

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