Concordant association validates MGMT methylation and protein expression as favorable prognostic factors in glioma patients on alkylating chemotherapy (Temozolomide).

Sci Rep · 2018 · PMC5928198 · PMID 29712977

Europe PMC DOI

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highly significantp = 0.000not a probability at all

An important finding from this study is the highly significant concordance between the status of MGMT methylation and its in situ protein expression by IHC (63% MGMT hypermethylation v/s 60% loss of MGMT protein; p = 0.000).

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