For example, TNFAIP8 mRNA expression was down-regulated in cancer (NSCLC) infiltrating CD4 + CD8 + T cells 35 , whereas others observed an increasing trend of TNFAIP8 mRNA level in tumor (papillary thyroid carcinoma) infiltrating CD4 + CD8 + T cells 45 .
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Tumor Necrosis Factor-α Induced Protein 8: Pathophysiology, Clinical Significance, and Regulatory Mechanism.
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