Prospective evaluation of plasma Epstein-Barr virus DNA clearance and fluorodeoxyglucose positron emission scan in assessing early response to chemotherapy in patients with advanced or recurrent nasopharyngeal carcinoma.

Despite the differences, the current study showed that pEBV DNA clearance of 8 days, 10 days, and 15 days all showed either a statistical trend or significant association with OS in the univariate analysis (Supplemental Table 1 ).

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However, a post-hoc subgroup analysis found that the dual endpoint remained significantly associated with OS in the palliative subgroup, while a nonsignificant trend was observed with PFS.

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