Analysis of the <i>in vitro</i> degradation and the <i>in vivo</i> tissue response to bi-layered 3D-printed scaffolds combining PLA and biphasic PLA/bioglass components - Guidance of the inflammatory response as basis for osteochondral regeneration.

Statistical differences were designated as significant if p-values were less than 0.05 (*p ≤ 0.05), and highly significant if P-values were less than 0.01 (**p ≤ 0.01) or less than 0.001 (***p ≤ 0.001). 3 Results 3.1 Scaffold structure Fig. 1 summarizes the structures of the studied scaffolds, namely PLA, PLA/G5 and the bi-layered scaffolds.

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