Beyond intention-to-treat: The effect of brief counseling for tobacco cessation in secondary analyses of a cluster randomized controlled trial in Swedish dental clinics.

None of the baseline characteristics differed at a statistically significant level between patients treated and not treated “as-intended”; only previous quit attempts differed statistically at borderline significance level, those with at least one quit attempt being more likely to receive the “as-intended” intervention compared with those who had no previous quit attempt (90.6% vs.81%, p = 0.054) ( Table 2 ).

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The intervention “as-intended” was associated with a marginally significant increased likelihood of making at least one quit attempt ( Table 3 ). 3.2.2 As-treated (AT) analysis The receipt of any combination of 4 A's or of 5 A's was associated with significantly increased odds of reduction by half of tobacco consumed daily when compared with no tobacco counseling, in the crude model and after discounting for readiness to quit and time to tobacco use after awakening.

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