Digitizing omics profiles by divergence from a baseline.

In all cases, the difference in the level of divergence between normal and tumor samples in each tissue and platform cohort is highly significant (Wilcoxon P value < 10 − 6 ; see Fig. 2 ).

also in 132,142 other papers

This revealed an increasing trend in average divergence from the normal baseline, strongly suggesting that divergence analysis can efficiently capture the global dysregulation associated with cancer progression or risk factor exposure.

also in 63,971 other papers