H3K4 Methylation Dependent and Independent Chromatin Regulation by <i>JHD2</i> and <i>SET1</i> in Budding Yeast.

In WT and jhd2 ∆ cells with normal SPT6 function, the H3 ChIP profiles were nearly superimposable throughout the entire SRG1 - SER3 region with one conspicuous exception: jhd2 ∆ caused a highly significant increase in H3 abundance at a single distinctive peak near the 3′ end of the SRG1 transcript unit, presumably reflecting a well-positioned nucleosome ( Figure 5B , peak denoted with a red asterisk, P < 0.05).

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