Barely Significant
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DNA methylation in the APOE genomic region is associated with cognitive function in African Americans.

BMC Med Genomics · 2018 · PMC5941603 · PMID 29739406

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marginal significanceP = 0.05actually significant
When we repeated the analysis for the eight significant CpG sites in the subset sample with available genotypes ( N = 242), all eight CpG sites remained significant at P < 0.05, except for APOE cg04406254 with a marginal significance ( P = 0.05), and effect estimates for some CpGs were slightly attenuated after adjustment for APOE ε4 carrier status (Additional file 1 : Table S1).

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