Low circulating total adiponectin, especially its non-high-molecular weight fraction, represents a promising risk factor for colorectal cancer: a meta-analysis.

Onco Targets Ther · 2018 · PMC5942166 · PMID 29765231

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markedly significantno p-value reported

In addition, the association of total adiponectin with colorectal cancer was markedly significant in studies with a nested case–control design and a large sample size, relative to studies with a retrospective case–control design and a small sample size, indicating the robustness of our observation.

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