Identification of a neutrophil-related gene expression signature that is enriched in adult systemic lupus erythematosus patients with active nephritis: Clinical/pathologic associations and etiologic mechanisms.

At lower doses of prednisone, ALN patients retained a trend to higher neutrophil scores that was marginally significant ( Fig 2C ), suggesting that both the ALN disease state itself and the higher doses of GCS treatment used to treat ALN contribute to the elevations of neutrophil scores observed.

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