What are the odds of anxiety disorders running in families? A family study of anxiety disorders in mothers, fathers, and siblings of children with anxiety disorders.

For current depressive disorder, a trend towards significance was found for mothers of children with AD compared to children of the control group (OR 5.35, 95% CI 0.67–42.65, p = 0.057), and no difference between children with ADs and controls was found for fathers (OR 0.26, 95% CI 0.03–1.99, p = 0.097). 1 Specificity and familial risk Table 3 displays the results regarding parents’ and siblings’ risk for a specific (same) AD as predicted by the child’s specific AD.

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Regarding (I), as compared to controls, children with ADs were respectively two and three times more likely to have at least one parent with lifetime and current ADs; two-and-a-half times more likely to have a mother with current ADs; nearly three times more likely to have a father with lifetime ADs, and—although borderline significant—four times more likely to have fathers with current ADs.

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