As expected, there was a nonsignificant trend for all treated subjects who are overweight/obese to have an elevated HOMA-IR score (Supplementary Materials S1 ).
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Mechanism Underlying Tissue Cryotherapy to Combat Obesity/Overweight: Triggering Thermogenesis.
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The sentences
There was a small trend towards a reduction in cryotreatment-induced weight and BMI changes as a function of age, although the trend was not statistically significant ( p ≅0.2): some older individuals displayed substantial reductions in waist circumference and some young subjects displayed low responses (not presented).