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A rapid solution-based method for determining the affinity of heroin hapten-induced antibodies to heroin, its metabolites, and other opioids.

Anal Bioanal Chem · 2018 · PMC5956019 · PMID 29675707

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an interesting trendno p-value reported
The effect of substituting a hydroxy group at different positions revealed an interesting trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.