Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking.

Nat Commun · 2018 · PMC5959879 · PMID 29777108

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highly significantno p-value reported

Intriguingly, this result matched an IPA screening of the TCGA “survival genes”, which also revealed that TNFα ( P < 10 −34 ) and NFκB ( P < 10 −11 ) were highly significant and interconnected upstream drivers of the IM chemokines (Fig. 4b , Supplementary Data 9 ).

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