Introduction In recent years, COPD has shown an increasing trend in morbidity and mortality rate compared to other diseases. 1 Its incidence has increased in developing countries and is an important socioeconomic burden for these countries. 1 Although smoking is considered to be the leading cause of COPD (which is characterized by completely nonreversible and often progressive airflow obstruction), only 15% of smokers develop COPD, 1 suggesting that other factors contribute to the formation of the disease.
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The effects of home oxygen therapy on energy metabolism in patients with COPD.
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