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Can crocin play a preventive role in Wistar rats with carbon tetrachloride-induced nephrotoxicity?

Iran J Basic Med Sci · 2018 · PMC5960754 · PMID 29796221

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an increasing trendno p-value reported
Determination of the adverse effects of synthetic drugs on public health led to an increasing trend of application of plants with medicinal properties as synthetic drug alternatives ( 14 , 15 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.